ChemInform Abstract: 1-Allyl- and 1-Benzyl-3-methyl-1,2,3-triazolium Salts via Tandem Click Transformations.

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  • ChemInform 2011, 42, issue 06

    View this journal online at

    wileyonlinelibrary.com

    Triazole derivativesR 0280 DOI: 10.1002/chin.201106153

    1-Allyl- and 1-Benzyl-3-methyl-1,2,3-triazolium Salts via Tandem Click Transfor-mations. Triazoles of type (III) are synthesized in a one-pot manner via 1,3-dipolar cycloaddition of terminal alkynes bearing an alkyl chain and organic azides, generated in situ. Methylation yields triazolium iodides which are viscous liquids with stable shelf life. Triazoles resulting from sterically hindered alkynes (R1:-tBu or -Ph) reveal only marginal conversion to the salts. (FLECHTER*, J. T.; KEENEY, M. E.; WALZ, S. E.; Synthesis 2010, 19, 3339-3345, http://dx.doi.org/10.1055/s-0030-1257909 ; Dep. Chem., Creighton Univ., Omaha, NE 68178, USA; Eng.) Mais

    06- 153 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

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